Mianserin

Description: Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family. Mianserin has antidepressant, antianxiety, antiemetic, hypotrophic, hypnotic and antihistamine effects, and can be used as a combination of norepinephrine and specific serotonin to treat depression. Target: Histamine Receptor. Smiles: CN1CC2N(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1. References: Blier P, et al. Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology (Berl). 1984,84(2):242-249.