Methoxyfenozide

Methoxyfenozide is a diacylhydrazine insecticide. It selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Dietary administration of methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s = 0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively). It induces early molting in O. nubilalis neonatal larvae when used at concentrations ranging from 0.063 to 0.5 ppm. Formulations containing methoxyfenozide have been used as insecticides in agriculture.Formal Name: 3-methoxy-2-methyl-benzoic acid, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide. CAS Number: 161050-58-4. Synonyms: RG-102398, RH-2485. Molecular Formula: C22H28N2O3. Formula Weight: 368.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMF:PBS (pH 7.2) (1:6): 0.1 mg/ml, DMSO: 20 mg/ml, Ethanol: 10 mg/ml. SMILES: COC1=CC=CC(C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)=O)=C1C. InChi Code: InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25). InChi Key: QCAWEPFNJXQPAN-UHFFFAOYSA-N.