Merestinib

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T3455-1mg	1 mg	7 - 10 Werktage*	45,00 €
TGM-T3455-2mg	2 mg	7 - 10 Werktage*	63,00 €
TGM-T3455-5mg	5 mg	7 - 10 Werktage*	106,00 €
TGM-T3455-1mL	1 ml	7 - 10 Werktage*	128,00 €
TGM-T3455-10mg	10 mg	7 - 10 Werktage*	145,00 €
TGM-T3455-25mg	25 mg	7 - 10 Werktage*	266,00 €
TGM-T3455-50mg	50 mg	7 - 10 Werktage*	445,00 €
TGM-T3455-100mg	100 mg	7 - 10 Werktage*	636,00 €
TGM-T3455-500mg	500 mg	7 - 10 Werktage*	1.330,00 €

Bei Fragen nutzen Sie gerne unser Kontaktformular.
Bestellen Sie auch per E-Mail: info@biomol.com
Größere Menge gewünscht? Bulk-Anfrage

Description: Merestinib (LY2801653) is an orally available, small molecule inhibitor of the... mehr

Menü schließen

Produktinformationen "Merestinib"

Description: Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein. Target: Discoidin Domain Receptor (DDR), c-Met/HGFR, ROS Kinase, ROS, FLT. Smiles: O(C1=C(C=C2C(=C1)C=NN2C)C=3C=NNC3)C4=C(F)C=C(NC(=O)C=5C(=O)N(C(C)=CC5)C6=CC=C(F)C=C6)C=C4. References: Yan SB, et al. Invest New Drugs. 2013, 31(4):833-44.

Schlagworte:	LY2801653
Hersteller:	TargetMol
Hersteller-Nr:	T3455

Eigenschaften

Anwendung:	Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR)
MW:	552.53 D
Formel:	C30H22F2N6O3

Datenbank Information

CAS :	1206799-15-6\| Passende Produkte
KEGG ID :	K04372 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H302, H351, H360, H372
P-Sätze:	P201, P202, P260, P264, P270, P280, P314, P330, P301+P310, P308+P313, P405, P501