Melatonin

Description: Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. Target: Apoptosis, CaMK, Estrogen/progestogen Receptor, ROR, Autophagy, Glutathione Peroxidase, Mitophagy, Melatonin Receptor, Endogenous Metabolite. Smiles: COC1=CC=C2NC=C(CCNC(C)=O)C2=C1. References: Reiter RJ, et al. J Biomed Sci, 2000, 7(6), 444-458.