Marein

Description: Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy. Target: HDAC, Akt, transporter, AMPK. Smiles: OC[C@H]1O[C@@H](Oc2ccc(C(=O)\C=C\c3ccc(O)c(O)c3)c(O)c2O)[C@H](O)[C@@H](O)[C@@H]1O. References: Marein protects against methylglyoxal-induced apoptosis by activating the AMPK pathway in PC12 cells.Free Radic Res. 2016,50(11):1173-1187.