m-3M3FBS

m-3M3FBS is an activator of phospholipase C (PLC) that stimulates superoxide generation, increase in cytoplasmic calcium, and inositol phosphate formation in human neutrophils when used at a concentration of 15-50 µM. It stimulates cytoplasmic calcium increases in several cell lines and, at 25 µM in vitro, promotes the hydrolysis of phosphatidylinositol bisphosphate by all PLC isoforms. m-3M3FBS is used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122 (Cay-70740).Formal Name: 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide. CAS Number: 200933-14-8. Molecular Formula: C16H16F3NO2S. Formula Weight: 343.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml. lambdamax: 230 nm. SMILES: O=S(NC1=CC(C(F)(F)F)=CC=C1)(C2=C(C)C=C(C)C=C2C)=O. InChi Code: InChI=1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3. InChi Key: ZIIUUSVHCHPIQD-UHFFFAOYSA-N.