(±)-LY367385

(±)-LY367385 is an antagonist of metabotropic glutamate receptor 1alpha (mGluR1alpha). It inhibits phosphoinositide (PI) hydrolysis selectively in AV-12 cells expressing mGluR1alpha over those expressing mGluR5a (IC50s = 19 and >300 µM, respectively).Formal Name: alpha-amino-4-carboxy-2-methyl-benzeneacetic acid. CAS Number: 198419-90-8. Molecular Formula: C10H11NO4. Formula Weight: 209.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Water: 20 mg/ml. SMILES: OC(C(C1=C(C=C(C=C1)C(O)=O)C)N)=O. InChi Code: InChI=1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15). InChi Key: SGIKDIUCJAUSRD-UHFFFAOYSA-N.