LTURM 34

LTURM 34 is an inhibitor of DNA protein kinase (DNA-PK, IC50 = 0.034 µM). It is selective for DNA-PK over PI3Kalpha, PI3Kbeta, PI3Kgamma, and PI3Kdelta at 10 µM. LTURM 34 (10 µM) inhibits the growth of HOP-92, SNB-75, and UO-31 cancer cells.Formal Name: 8-(4-dibenzothienyl)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one. CAS Number: 1879887-96-3. Molecular Formula: C24H18N2O3S. Formula Weight: 414.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 5 mg/ml, DMSO: 2 mg/ml, Ethanol: insol, PBS (pH 7.2): insol. SMILES: O=C1N=C(N2CCOCC2)OC3=C(C4=C(SC5=CC=CC=C56)C6=CC=C4)C=CC=C31. InChi Code: InChI=1S/C24H18N2O3S/c27-23-19-9-3-6-16(21(19)29-24(25-23)26-11-13-28-14-12-26)18-8-4-7-17-15-5-1-2-10-20(15)30-22(17)18/h1-10H,11-14H2. InChi Key: SMMSWOMXOZLOPI-UHFFFAOYSA-N.