(±)-Liquiritigenin

Description: (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone), a flavonoid extracted from Angelica keiskei, inhibits the calcium-activated chloride channel TMEM16A.(±)-Liquiritigenin induces an increase in apoptosis and an enhancement of caspase3 activity. (±)-Liquiritigenin induces increased apoptosis and enhanced caspase3 activity. (±)-Liquiritigenin is used in breast cancer research. Target: Apoptosis, Calcium Channel. Smiles: Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1. References: Yun-Seo Kil, et al. Minor phenolics from Angelica keiskei and their proliferative effects on Hep3B cells. Bioorg Med Chem Lett. 2017 Jul 15,27(14):3065-3070.