Lexipafant

Description: Lexipafant is a platelet-activating factor (PAF) receptor antagonist which inhibits the binding of PAF to its receptor, thereby reducing inflammation and associated tissue injury. [Reduce organ damage, mitigate sepsis]. Target: Others. Smiles: C(N1C=2C(N=C1C)=CN=CC2)C3=CC=C(S(N([C@H](C(OCC)=O)CC(C)C)C)(=O)=O)C=C3. References: Oztürk H, Oztürk H, Dokucu AI, Otcu S. Effects of lexipafant (BB-882), a platelet activating factor receptor antagonist, on liver damage due to bile duct ligation in rats. Acta Gastroenterol Belg. 2006 Apr-Jun,69(2):197-202. PubMed PMID: 16929615.