Leptomycin B

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T15735-1mg	1 mg	7 - 10 Werktage*	212,00 €
TGM-T15735-1mL	1 ml	7 - 10 Werktage*	296,00 €
TGM-T15735-2mg	2 mg	7 - 10 Werktage*	365,00 €
TGM-T15735-5mg	5 mg	7 - 10 Werktage*	665,00 €
TGM-T15735-10mg	10 mg	7 - 10 Werktage*	946,00 €
TGM-T15735-25mg	25 mg	7 - 10 Werktage*	1.390,00 €
TGM-T15735-50mg	50 mg	7 - 10 Werktage*	1.909,00 €
TGM-T15735-100mg	100 mg	7 - 10 Werktage*	2.584,00 €

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Description: Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a... mehr

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Produktinformationen "Leptomycin B"

Description: Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Target: Antibiotic, Antifungal, CRM1. Smiles: CC\C(\C=C\[C@H]1OC(=O)C=C[C@@H]1C)=C\[C@H](C)C\C=C\C(\C)=C\[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C\C(C)=C\C(O)=O. References: Kudo N, et al. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci U S A. 1999 Aug 3,96(16):9112-7.

Schlagworte:	LMB, CI 940
Hersteller:	TargetMol
Hersteller-Nr:	T15735

Eigenschaften

Anwendung:	Nuclear export blocker
MW:	540.73 D
Formel:	C33H48O6

Datenbank Information

CAS :	87081-35-4\| Passende Produkte
KEGG ID :	K14290 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	+4°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H225, H301, H311, H331, H370
P-Sätze:	P210, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P303+P361+P353, P304+P340, P308+P311, P361+P364, P370+P378, P405, P403+P233, P403+P235, P501