Lactacystin

Induces neuritogenesis, Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP, multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit, apoptosis inducer, anticancer compound, upregulates HSP70 and HSP22, induces differentiation and inhibits cell cycle progression in several tumor cell lines, inhibits NF-kappaB activation by inhibiting IkappaB degradation, cathepsin A inhibitor, gamma-Secretase activity inhibitor, anti-adipogenic