L-Valine-d8

L-Valine-d8 is intended for use as an internal standard for the quantification of L-valine (Cay-38709) by GC- or LC-MS. L-Valine is a branched-chain essential amino acid that is obtained via the diet. It is considered glucogenic due to its catabolism that ultimately forms succinyl-CoA, which enters the citric acid cycle. A deficiency in branched-chain dehydrogenase, the enzyme that catabolizes valine, isoleucine, and leucine, leads to maple syrup urine disease, a disorder characterized by progressive ketoacidosis, failure to thrive, neurological dysfunction, and, potentially, death.Formal Name: L-valine-2,3,4,4,4,4',4',4'-d8. CAS Number: 35045-72-8. Synonyms: (+)-Valine, (S)-Valine. Molecular Formula: C5H3D8NO2. Formula Weight: 125.2. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 1 mg/ml. SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])[C@@](N)([2H])C(O)=O. InChi Code: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1/i1D3,2D3,3D,4D. InChi Key: KZSNJWFQEVHDMF-AYWPRJOCSA-N.