L-DOPA methyl ester (hydrochloride)

L-DOPA (Cay-13248) is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier to act as a dopamine D1 receptor agonist. It is produced from L-tyrosine by trysosine hydroxylase. In the brain, L-DOPA is converted to dopamine by the enzyme aromatic L-amino acid decarboxylase. It is conventionally used to increase dopamine concentrations in the brain as a treatment for Parkinson's disease and stroke recovery. L-DOPA methyl ester is a neutral derivative of L-DOPA formulated for increased solubility compared to the parent compound.Formal Name: 3-hydroxy-L-tyrosine, methyl ester, monohydrochloride. CAS Number: 1421-65-4. Synonyms: 3,4-Dihydroxyphenylalanine methyl ester, LDME, Levodopa methyl ester, ST 41769. Molecular Formula: C10H13NO4 . HCl. Formula Weight: 247.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 284 nm. SMILES: OC1=C(O)C=CC(C[C@H](N)C(OC)=O)=C1.Cl. InChi Code: InChI=1S/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6,/h2-3,5,7,12-13H,4,11H2,1H3,1H/t7-,/m0./s1. InChi Key: WFGNJLMSYIJWII-FJXQXJEOSA-N.