KRAS inhibitor-7

Description: KRAS inhibitor-7 is a potent inhibitor of KRAS G12C. (KRAS inhibitor-7 specifically targets the G12C mutation in KRAS, a protein involved in cell signaling and cancer development.) [KRAS inhibitor-7 exhibits high binding affinity and selectivity for the mutant KRAS protein.]. Target: Ras. Smiles: FC=1C2=C(C(=NC(=N2)N3CC(N(C)C)C3)N4CCN(C(C=C)=O)CC4)C=C(Cl)C1C5=C(F)C=CC=C5O. References: Liansheng Li, et al. 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof. WO2017087528A1.