JOSAMYCIN

Description: Josamycin (EN-141) is a macrolide antibiotic with antimicrobial activity, characterized by a ribosomal dissociation constant (Kd) of 5.5 nM. Target: Antibacterial, Antibiotic. Smiles: [H][C@@]1(C[C@@](C)(O)[C@@H](OC(=O)CC(C)C)[C@H](C)O1)O[C@@H]1[C@@H](C)O[C@@H](O[C@@]2([H])[C@@H](CC=O)C[C@@H](C)[C@@H](O)\C=C\C=C\C[C@@H](C)OC(=O)C[C@@H](OC(C)=O)[C@@H]2OC)[C@H](O)[C@H]1N(C)C. References: Eun-Young C , So-Hui C , Jin-Yi H , et al. Josamycin suppresses, Prevotella intermedia, lipopolysaccharide-induced production of nitric oxide and interleukin-1beta in murine macrophages[J]. Biomedicine & Pharmacotherapy, 2018, 105:498-505.