Isobavachalcone

Description: Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation. Target: Autophagy, Apoptosis, Akt, Reactive Oxygen Species, Others. Smiles: CC(C)=CCc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2)c1O. References: Lee KM,et al. Isobavachalcone attenuates lipopolysaccharide-induced ICAM-1 expression in brain endothelial cells through blockade of toll-like receptor 4 signaling pathways. Eur J Pharmacol. 2015 May 5,754:11-8.