IMP-1088

IMP-1088 is an inhibitor of N-myristoyltransferase 1 (NMT1) and NMT2 (IC50 = 50 = >1,000 nM). It also blocks production of infectious RV-16 virus in primary human bronchial epithelial cells (hBECs) when added 3 hours post infection via inhibition of viral capsid assembly.Formal Name: 5-[3,4-difluoro-2-[2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethoxy]phenyl]-N,N,1-trimethyl-1H-indazole-3-methanamine. CAS Number: 2059148-82-0. Molecular Formula: C25H29F2N5O. Formula Weight: 453.5. Purity: >95%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: Methyl Acetate: 10 mg/ml. lambdamax: 217, 244, 305 nm. SMILES: FC1=C(F)C=CC(C2=CC=C(N(C)N=C3CN(C)C)C3=C2)=C1OCCC4=C(C)N(C)N=C4C. InChi Code: InChI=1S/C25H29F2N5O/c1-15-18(16(2)31(5)28-15)11-12-33-25-19(8-9-21(26)24(25)27)17-7-10-23-20(13-17)22(14-30(3)4)29-32(23)6/h7-10,13H,11-12,14H2,1-6H3. InChi Key: SOXNKJCQBRQUMS-UHFFFAOYSA-N.