ICI 118551 (hydrochloride)

ICI 118551 is a potent, selective antagonist of the beta2-adrenergic receptor (Ki = 0.7 nM for the beta2 receptor, compared with 49.5 and 611 nM for beta1 and beta3 receptors, respectively). It is active in vivo and is often used to evaluate the actions of adrenergic receptor agonists.Formal Name: (2R,3R)-rel-1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol, monohydrochloride. CAS Number: 72795-01-8. Molecular Formula: C17H27NO2 . HCl. Formula Weight: 313.9. Purity: >99%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml, DMSO: 3 mg/ml, Ethanol: 2 mg/ml. SMILES: CC1=C(CCC2)C2=C(OC[C@H](O)[C@@H](C)NC(C)C)C=C1.Cl. InChi Code: InChI=1S/C17H27NO2.ClH/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17,/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3,1H/t13-,16+,/m1./s1. InChi Key: KBXMBGWSOLBOQM-CACIRBSMSA-N.