Hymeglusin

Description: Hymeglusin, A selective 3-hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) synthase 1 inhibitor, is also an antibiotic that reduces the expression level of BCL2 in HL-60 and KG-1 cells and can be used to study leukemia. Target: Antibiotic. Smiles: C(O)[C@@H]1[C@@H](CCCC[C@H](C/C(=C/C(=C/C(O)=O)/C)/C)C)OC1=O. References: Rothwell C, et al. Cholesterol biosynthesis modulation regulates dengue viral replication. Virology. 2009 Jun 20,389(1-2):18-19.