Hydrochlorothiazide Impurity C

Hydrochlorothiazide impurity C is a potential impurity found in commercial hydrochlorothiazide preparations. Hydrochlorothiazide (Cay-21304) is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter in the distal and collecting duct nephron segments.Formal Name: N-[[7-(aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxido-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide. CAS Number: 402824-96-8. Molecular Formula: C15H16Cl2N6O8S4. Formula Weight: 607.5. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: O=S1(C2=CC(S(NCN3C(C=C(Cl)C(S(N)(=O)=O)=C4)=C4S(NC3)(=O)=O)(=O)=O)=C(Cl)C=C2NCN1)=O. InChi Code: InChI=1S/C15H16Cl2N6O8S4/c16-8-1-10-14(34(28,29)20-5-19-10)4-13(8)33(26,27)21-6-23-7-22-35(30,31)15-3-12(32(18,24)25)9(17)2-11(15)23/h1-4,19-22H,5-7H2,(H2,18,24,25). InChi Key: ARZJHXODDVTRLY-UHFFFAOYSA-N.