GSK3beta Inhibitor XI

GSK3beta inhibitor XI is a potent inhibitor of glycogen synthase kinase 3beta (GSK3beta, Ki = 25 nM). It is selective for GSK3beta over a panel of 79 kinases at a concentration of 10 µM. GSK3beta inhibitor XI inhibits GSK3beta in HEK293 cells (EC50 = 32 nM).Formal Name: 3-[1-(3-hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-(2-pyrazinyl)-1H-pyrrole-2,5-dione. CAS Number: 626604-39-5. Molecular Formula: C18H15N5O3. Formula Weight: 349.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 5 mg/ml. SMILES: O=C(N1)C(C2=CN=CC=N2)=C(C3=CN(CCCO)C4=C3C=CC=N4)C1=O. InChi Code: InChI=1S/C18H15N5O3/c24-8-2-7-23-10-12(11-3-1-4-21-16(11)23)14-15(18(26)22-17(14)25)13-9-19-5-6-20-13/h1,3-6,9-10,24H,2,7-8H2,(H,22,25,26). InChi Key: ZDEJZKULWCZIHL-UHFFFAOYSA-N.