GSK2981278

Description: GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma). Target: ROR. Smiles: CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)c(CO)c1. References: Birault Veronique, et al. Preparation of tetrahydropyranylmethoxy benzenesulfonamide compounds as RORgamma modulators useful in therapy of various diseases. From PCT Int. Appl. (2015), WO 2015061515 A1 20150430.