Glycochenodeoxycholic Acid (sodium salt hydrate)

Glycochenodeoxycholic Acid (sodium salt hydrate)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay16942-25 25 mg -

6 - 10 Werktage*

43,00 €
Cay16942-50 50 mg -

6 - 10 Werktage*

65,00 €
Cay16942-100 100 mg -

6 - 10 Werktage*

77,00 €
Cay16942-500 500 mg -

6 - 10 Werktage*

246,00 €
 
Glycochenodeoxycholic acid (GCDCA) is a glycine-conjugated form of the primary bile acid... mehr
Produktinformationen "Glycochenodeoxycholic Acid (sodium salt hydrate)"
Glycochenodeoxycholic acid (GCDCA) is a glycine-conjugated form of the primary bile acid chenodeoxycholic acid (Cay-10011286). It reduces formation of cholic acid (Cay-20250) in primary human hepatocytes when used at a concentration of 100 µM. GCDCA (50, 75, and 100 µM) reduces the number of LC3 puncta, a marker of autophagy, and is cytotoxic to L-02 hepatocytes. GCDCA (50 µM) induces apoptosis in isolated rat hepatocytes, an effect that can be blocked by the protein kinase C (PKC) inhibitor chelerythrine (Cay-11314). Fecal levels of GCDCA are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.Formal Name: N-[(3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl]-glycine, monosodium salt, hydrate. Synonyms: GCDCA, NSC 681056. Molecular Formula: C26H42NO5 . Na [XH2O]. Formula Weight: 471.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, Ethanol: 15 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H]1CC[C@@]2(C)[C@@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(NCC([O-])=O)=O)([H])C1.[Na+].O. InChi Code: InChI=1S/C26H43NO5.Na.H2O/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29,,/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32),,1H2/q,+1,/p-1/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-,,/m1../s1. InChi Key: DPKVEQOULFKWCR-KZRRTRIISA-M.
Schlagworte: GCDCA, NSC 681056, N-[(3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl]-glycine, monosodium salt, hydrate
Hersteller: Cayman Chemical
Hersteller-Nr: 16942

Eigenschaften

Anwendung: Biosurfactant
MW: 471.6 D
Formel: C26H42NO5 . Na [XH2O]
Reinheit: >95%
Format: Crystalline Solid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Glycochenodeoxycholic Acid (sodium salt hydrate)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen