GLP-1R Modulator L7-028

GLP-1R modulator L7-028 is a positive allosteric modulator of the glucagon-like peptide 1 receptor (GLP-1R). It enhances GLP-1 binding to GLP-1R (EC50 = 11.01 µM) and cAMP accumulation induced by GLP-1 (7-36) in CHO cells expressing GLP-1R.Formal Name: N,N,6-triethyl-9,10-didehydro-1-(1-oxopropyl)-ergoline-8beta-carboxamide. CAS Number: 2648317-95-5. Synonyms: GLP-1 Receptor Modulator L7-028, Glucagon-like Peptide 1 Receptor Modulator L7-028. Molecular Formula: C24H28N2O3. Formula Weight: 392.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble: >10 mg/ml, Ethanol: Sparingly soluble: 1-10 mg/ml. SMILES: O=C(C1=CC(OC2CCCC2)=CC=C1)NC3=CC=CC(C(N4CCCCC4)=O)=C3. InChi Code: InChI=1S/C24H28N2O3/c27-23(18-8-7-13-22(17-18)29-21-11-2-3-12-21)25-20-10-6-9-19(16-20)24(28)26-14-4-1-5-15-26/h6-10,13,16-17,21H,1-5,11-12,14-15H2,(H,25,27). InChi Key: QASJOTNVPCHDTC-UHFFFAOYSA-N.