GLP-1R Agonist DMB

Description: GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R, KB = 26.3 nM for the recombinant human receptor). Target: Glucagon Receptor. Smiles: CC(C)(C)Nc1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O. References: Koole, C., Wootten, D., Simms, J., et al. Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: Implications for drug screening. Mol. Pharmacol. 78(3), 456-465 (2010).