Ginsenoside Re

Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Re is a panaxatriol saponin that is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions. Ginsenoside Re improves the effectiveness of chemotherapeutic agents by decreasing the expression of Multidrug Resistance Protein 1 and inhibiting P-glycoprotein. Notably, this ginsenoside is converted to other forms in response to steaming or heating plant materials, leading to loss of activity.Formal Name: (6alpha)-20-(beta-D-glucopyranosyloxy)-3beta,12beta-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside. CAS Number: 52286-59-6. Synonyms: Chikusetsusaponin IVc, NSC 308877, Panaxoside Re, Sanchinoside Re. Molecular Formula: C48H82O18. Formula Weight: 947.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml, DMSO: 15 mg/ml, Ethanol: 5 mg/ml. SMILES: O[C@H]1[C@@]2([H])[C@](CC[C@]2([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)(C)[C@]4(C)C[C@H](O[C@@]5([H])[C@H](O[C@@]6([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@]7([H])[C@@](CC[C@H](O)C7(C)C)(C)[C@@]4([H])C1. InChi Code: InChI=1S/C48H82O18/c1-21(2)11-10-14-48(9,66-42-38(60)35(57)32(54)26(19-49)63-42)23-12-16-46(7)30(23)24(51)17-28-45(6)15-13-29(52)44(4,5)40(45)25(18-47(28,46)8)62-43-39(36(58)33(55)27(20-50)64-43)65-41-37(59)34(56)31(53)22(3)61-41/h11,22-43,49-60H,10,12-20H2,1-9H3/t22-,23-,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,43+,45+,46+,47+,48-/m0/s1. InChi Key: PWAOOJDMFUQOKB-WCZZMFLVSA-N.