Ginkgolide C

Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist (IC50 = 37.6 µM). Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes via the activated AMPK pathway.Formal Name: (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-dimethylethyl)hexahydro-2,4,7b,11-tetrahydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione. CAS Number: 15291-76-6. Synonyms: BN 52022, 1,7-dihydroxy Ginkgolide A. Molecular Formula: C20H24O11. Formula Weight: 440.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/mL, DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL, DMSO: 14 mg/mL. SMILES: O=C(O1)[C@@H](C)[C@@]2(O)[C@]1([H])[C@H](O)C34[C@@]25O[C@@]6([H])C3([C@@H](O)C(O6)=O)[C@H](C(C)(C)C)[C@@H](O)[C@H]4OC5=O. InChi Code: InChI=1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3/t5-,6-,7+,8+,9+,10-,11+,15+,17?,18?,19-,20-/m1/s1. InChi Key: AMOGMTLMADGEOQ-AEXCBEIUSA-N.