Gemifloxacin mesylate

Description: Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of gemifloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. This fluoroquinolone exerts an enhanced spectrum of activity against gram-positive bacteria such as Streptococcus pneumonia and Staphylococcus aureus, in addition to its activity against gram-negative bacteria. Target: Topoisomerase, Antibacterial, DNA gyrase. Smiles: CS(O)(=O)=O.CO\N=C1\CN(CC1CN)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1. References: Ruiz J, et al. Int J Antimicrob Agents. 2003 Jul,22(1):73-6.