Flecainide (acetate)

Flecainide is an inhibitor of cardiac late sodium current (INa, IC50 = 3.4 µM) and delayed-rectifier potassium current (IKr, IC50 = 1.5 µM). Formulations containing flecainide have been used in the treatment of arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure.Formal Name: N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-benzamide, monoacetate. CAS Number: 54143-56-5. Molecular Formula: C17H20F6N2O3 . C2H4O2. Formula Weight: 474.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 100mM, Water: 25mM. lambdamax: 261 nm. SMILES: O=C(NCC1CCCCN1)C2=C(OCC(F)(F)F)C=CC(OCC(F)(F)F)=C2.OC(C)=O. InChi Code: InChI=1S/C17H20F6N2O3.C2H4O2/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11,1-2(3)4/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26),1H3,(H,3,4). InChi Key: RKXNZRPQSOPPRN-UHFFFAOYSA-N.