(-)-Epigallocatechin

(-)-Epigallocatechin ((-)-EGC) is a major green tea polyphenol with antioxidant, anti-inflammatory, and anticancer activities. It has been shown to scavenge DPPH radicals with an EC50 value of 0.01 mM and to prevent the growth of several different AML cell lines at micromolar concentrations. Furthermore, at 30 µM (-)-EGC can inhibit heregulin-beta1-induced migration/invasion of MCF-7 human breast cancer cells.Formal Name: (2R,3R)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol. CAS Number: 970-74-1. Synonyms: (-)-EGC, epi-Gallocatechin, NSC 674039. Molecular Formula: C15H14O7. Formula Weight: 306.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 15 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 209 nm. SMILES: OC1=CC2=C(C[C@@H](O)[C@@H](C3=CC(O)=C(O)C(O)=C3)O2)C(O)=C1. InChi Code: InChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1. InChi Key: XMOCLSLCDHWDHP-IUODEOHRSA-N.