Ensartinib

Description: Ensartinib (X-396) is a potent dual ALK/MET inhibitor with IC50 values of <0.4 nM for ALK and 0.74 nM for MET. Target: Others. Smiles: C(=O)(N1C[C@@H](C)N[C@@H](C)C1)C2=CC=C(NC(=O)C3=CC(O[C@H](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=N3)C=C2. References: Lovly CM, et al. Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinaseinhibitors. Cancer Res. 2011 Jul 15,71(14):4920-31.