Enalaprilat

Description: Enalaprilat, the active metabolite of Enalapril, is a effective intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. Target: Others. Smiles: C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O. References: Ferslew BC, Köck K, Bridges AS, Brouwer KL. Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat. Drug Metab Dispos. 2014 Sep,42(9):1567-74. doi: 10.1124/dmd.114.057554. Epub 2014 Jun 23. PubMed PMID: 24958844, PubMed Central PMCID: PMC4152871.