(E)-Naringenin chalcone

Description: Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid that improves adipocyte metabolic functions and exerts insulin-sensitizing effects by activating an adiponectin-related pathway. Naringenin chalcone exhibits anti-inflammatory properties by inhibiting the production of proinflammatory cytokines in the interaction between adipocytes and macrophages, may be useful for ameliorating the inflammatory changes in obese adipose tissue. Target: Others. Smiles: Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)cc1. References: Horiba T , Nishimura I , Nakai Y , et al. Naringenin chalcone improves adipocyte functions by enhancing adiponectin production[J]. Molecular & Cellular Endocrinology, 2010, 323(2):208-214.