DUPA

DUPA is an inhibitor of prostate-specific membrane antigen (PSMA, IC50 = 47 nM for the glutamate carboxypeptidase activity). It has been used as a ligand to target radiolabels, cytotoxic agents, and antibody-drug conjugates to cancer cells.Formal Name: N,N'-carbonylbis-L-glutamic acid. CAS Number: 302941-52-2. Molecular Formula: C11H16N2O9. Formula Weight: 320.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Sparingly soluble: 1-10 mg/ml, Ethanol: Sparingly soluble: 1-10 mg/ml, PBS (pH 7.2): Sparingly soluble: 1-10 mg/ml. SMILES: O=C(O)[C@@H](NC(N[C@H](C(O)=O)CCC(O)=O)=O)CCC(O)=O. InChi Code: InChI=1S/C11H16N2O9/c14-7(15)3-1-5(9(18)19)12-11(22)13-6(10(20)21)2-4-8(16)17/h5-6H,1-4H2,(H,14,15)(H,16,17)(H,18,19)(H,20,21)(H2,12,13,22)/t5-,6-/m0/s1. InChi Key: SOAPXKSPJAZNGO-WDSKDSINSA-N.