Doxycycline-d3 (hyclate)

Doxycycline-d3 (hyclate)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay28528-1 1 mg -

6 - 10 Werktage*

432,00 €
 
Doxycycline-d3 is intended for use as an internal standard for the quantification of doxycycline... mehr
Produktinformationen "Doxycycline-d3 (hyclate)"
Doxycycline-d3 is intended for use as an internal standard for the quantification of doxycycline (Cay-14422) by GC- or LC-MS. Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 µM. It can be used as a regulator for inducible gene expression systems where expression depends on either the presence (Tet-On) or absence (Tet-Off) of doxycycline. Formulations containing doxycycline have been used in the treatment of bacterial infections and the prevention of malaria.Formal Name: (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-(6-methyl-d)-1,11-dioxo-2-naphthacene-4,6-d2-carboxamide, hydrochloride, compd. with ethanol, hydrate (2:2:1:X). Molecular Formula: 2[C22H21D3N2O8] . 2HCl . XH2O . C2H6O. Formula Weight: 894.9. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble. SMILES: CCO.OC1=C2C([C@@](C([2H])([H])[H])([2H])[C@]3([H])C(C2=O)=C(O)[C@@]4(O)[C@@]([C@@](N(C)C)([2H])C(O)=C(C(N)=O)C4=O)([H])[C@H]3O)=CC=C1.OC5=C6C([C@@](C([2H])([H])[H])([2H])[C@]7([H])C(C6=O)=C(O)[C@@]8(O)[C@@]([C@@](N(C)C)([2H])C(O)=C(C(N)=O)C8=O)([H])[C@H]7O)=CC=C5.Cl.O.Cl. InChi Code: InChI=1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29,1-2-3,,,/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31),3H,2H2,1H3,2*1H,1H2/t2*7-,10+,14+,15-,17-,22-,,,,/m00..../s1/i2*1D,7D,15D,,,,. InChi Key: HALQELOKLVRWRI-SFNMZOGZSA-N.
Schlagworte: (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-(6-methyl-d)-1,11-dioxo-2-naphthacene-4,6-d2-carboxamide, hydrochloride, compd. with ethanol, hydrate (2:2:1:X)
Hersteller: Cayman Chemical
Hersteller-Nr: 28528

Eigenschaften

Anwendung: GC-MS, LC-MS, Internal standard, Quantification, Antibacterial, Protein biosynthesis inhibitor
MW: 894.9 D
Formel: 2[C22H21D3N2O8] . 2HCl . XH2O . C2H6O
Reinheit: >99% deuterated forms (d1-d3)
Format: Solid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302, H315, H319, H335
P-Sätze: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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