Dovitinib lactate hydrate

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T6479-5mg	5 mg	7 - 10 Werktage*	49,00 €
TGM-T6479-1mL	1 ml	7 - 10 Werktage*	49,00 €
TGM-T6479-10mg	10 mg	7 - 10 Werktage*	75,00 €
TGM-T6479-25mg	25 mg	7 - 10 Werktage*	142,00 €
TGM-T6479-50mg	50 mg	7 - 10 Werktage*	242,00 €
TGM-T6479-100mg	100 mg	7 - 10 Werktage*	403,00 €
TGM-T6479-200mg	200 mg	7 - 10 Werktage*	587,00 €

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Description: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a... mehr

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Produktinformationen "Dovitinib lactate hydrate"

Description: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. Target: FLT, PDGFR, VEGFR, FGFR, c-Kit. Smiles: O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O. References: Trudel S, et al. Blood, 2005, 105(7), 2941-2948.

Schlagworte:	Dovitinib (TKI258) Lactate, Dovitinib Lactate, TKI258
Hersteller:	TargetMol
Hersteller-Nr:	T6479

Eigenschaften

Anwendung:	Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135)
MW:	482.51 D
Formel:	C24H27FN6O4

Datenbank Information

CAS :	915769-50-5\| Passende Produkte
KEGG ID :	K05089 \| Passende Produkte
Protein Atlas Nr. :	Tyrosine Phosphorylation

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H302, H341, H351, H361, H372, H400, H410
P-Sätze:	P201, P202, P260, P264, P270, P273, P280, P314, P330, P391, P301+P310, P308+P313, P405, P501