DL-Homocysteine thiolactone (hydrochloride)

DL-Homocysteine thiolactone is a derivative of DL-homocysteine (Cay-30285). It inhibits the growth of B. campestris, L. sativa, and E. utilis roots when used at a concentration of 50 µM. DL-Homocysteine thiolactone (10 µM) decreases the maximum rate of left ventricular developed pressure, systolic left ventricular pressure, and coronary flow in isolated rat hearts. It induces arteriosclerotic plaque formation in rabbits when administered at a dose of 30 mg/kg for eight weeks. DL-Homocysteine thiolactone has also been used as a precursor in the synthesis of thiolactone-containing monomers for use in polymer-based formaldehyde-scavenging coatings.Formal Name: 3-aminodihydro-2(3H)-thiophenone, monohydrochloride. CAS Number: 6038-19-3. Synonyms: DL-Hcy thiolactone, DL-Hcy TLHC, NSC 22879. Molecular Formula: C4H7NOS . HCl. Formula Weight: 153.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 237 nm. SMILES: O=C1SCCC1N.Cl. InChi Code: InChI=1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6,/h3H,1-2,5H2,1H. InChi Key: ZSEGSUBKDDEALH-UHFFFAOYSA-N.