Dimethyl-W84 (dibromide)

Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor. It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor with an EC50 value of 3 nM.Formal Name: N1,N6-bis[3-(1,3-dihydro-5-methyl-1,3-dioxo-2H-isoindol-2-yl)propyl]-N1,N1,N6,N6-tetramethyl-1,6-hexanediaminium, dibromide. CAS Number: 402475-33-6. Molecular Formula: C34H48N4O4 . 2Br. Formula Weight: 736.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Water: soluble. SMILES: CC1=CC=C(C(N(CCC[N+](C)(C)CCCCCC[N+](C)(C)CCCN2C(C(C=C(C)C=C3)=C3C2=O)=O)C4=O)=O)C4=C1.[Br-].[Br-]. InChi Code: InChI=1S/C34H48N4O4.2BrH/c1-25-13-15-27-29(23-25)33(41)35(31(27)39)17-11-21-37(3,4)19-9-7-8-10-20-38(5,6)22-12-18-36-32(40)28-16-14-26(2)24-30(28)34(36)42,,/h13-16,23-24H,7-12,17-22H2,1-6H3,2*1H/q+2,,/p-2. InChi Key: JDKHHBPNUMYHFM-UHFFFAOYSA-L.