Dimenhydrinate

Dimenhydrinate is an antiemetic consisting of diphenhydramine (Cay-11158), a histamine H1 and muscarinic cholinergic receptor antagonist, and 8-chlorotheophylline, a derivative of the phosphodiesterase inhibitor and adenosine receptor antagonist theophylline (Cay-23760). Formulations containing dimenhydrinate have been used in the treatment of motion sickness.Formal Name: 8-chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione with 2-(diphenylmethoxy)-N,N-dimethylethanamine. CAS Number: 523-87-5. Synonyms: Diphenhydramine 8-chlorotheophylline, NSC 117855. Molecular Formula: C24H28ClN5O3. Formula Weight: 470.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble: >10 mg/ml, Ethanol: Sparingly Soluble: 1-10 mg/ml. SMILES: O=C(C(NC(Cl)=N1)=C1N2C)N(C)C2=O.CN(C)CCOC(C3=CC=CC=C3)C4=CC=CC=C4. InChi Code: InChI=1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16,1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3,1-2H3,(H,9,10). InChi Key: NFLLKCVHYJRNRH-UHFFFAOYSA-N.