Dihydrochelerythrine

Description: 1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5µM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application in the therapy of serious infection caused by I. multifiliis. 4. Dihydrochelerythrine affects cell cycle distribution, activates mitochondrial apoptotic pathway, and induces apoptosis and necrosis in HL-6 cells. Target: Antifungal. Smiles: COc1ccc-2c(CN(C)c3c-2ccc2cc4OCOc4cc32)c1OC. References: Feng G , Zhang J , Liu Y Q . Inhibitory activity of dihydrosanguinarine and dihydrochelerythrine against phytopathogenic fungi[J]. Natural Product Research, 2011, 25(11):1082-1089.