Diclofenac amide

Diclofenac amide
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay21969-50 50 mg -

6 - 10 Werktage*

48,00 €
Cay21969-100 100 mg -

6 - 10 Werktage*

89,00 €
Cay21969-500 500 mg -

6 - 10 Werktage*

368,00 €
Cay21969-1 1 g -

6 - 10 Werktage*

639,00 €
 
Diclofenac amide is a prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac... mehr
Produktinformationen "Diclofenac amide"
Diclofenac amide is a prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac (Cay-70680, Cay-22983). It decreases paw thickness in a rat model of carrageenan-induced paw edema when administered at a dose of 100 µmol/kg and decreases acetic acid-induced writhing in mice at 100 µmol/kg. Diclofenac amide has reduced ulcerogenicity in rats compared to diclofenac. It is also a degradation product of diclofenac resulting from photo-transformation or spontaneous cyclization in strongly acidic pH conditions. Diclofenac amide has been used as a synthetic intermediate in the synthesis of compounds with anticancer activity as well as compounds with COX-1, COX-2, and/or 5-lipoxygenase (5-LO) inhibitory activity.Formal Name: 1-(2,6-dichlorophenyl)-1,3-dihydro-2H-indol-2-one. CAS Number: 15362-40-0. Synonyms: Diclofenac Lactam, 1-(2,6-Dichlorophenyl)oxindole, NSC 621845. Molecular Formula: C14H9Cl2NO. Formula Weight: 278.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: >50mg/mL, DMSO: >40mg/mL, Ethanol: >35mg/mL, PBS (pH 7.2): >9mg/mL. SMILES: ClC1=C(N2C(CC3=C2C=CC=C3)=O)C(Cl)=CC=C1. InChi Code: InChI=1S/C14H9Cl2NO/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(17)18/h1-7H,8H2. InChi Key: JCICIFOYVSPMHG-UHFFFAOYSA-N.
Schlagworte: 1-(2,6-Dichlorophenyl)oxindole, Diclofenac Lactam, NSC 621845, 1-(2,6-dichlorophenyl)-1,3-dihydro-2H-indol-2-one
Hersteller: Cayman Chemical
Hersteller-Nr: 21969

Eigenschaften

Anwendung: NSAID prodrug
MW: 278.1 D
Formel: C14H9Cl2NO
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 15362-40-0| Passende Produkte
KEGG ID : K11987 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302, H315, H319, H335
P-Sätze: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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