Desethyl Hydroxychloroquine-d4

Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine (Cay-31152) by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Cay-17911). It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.Formal Name: 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-ethan-1,1,2,2-d4-ol. CAS Number: 1854126-47-8. Synonyms: Cletoquine-d4, (±)-Desethylhydroxychloroquine-d4, DHCQ-d4. Molecular Formula: C16H18ClD4N3O. Formula Weight: 311.8. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, DMSO: Soluble, Methanol: Soluble. SMILES: ClC1=CC2=C(C=C1)C(NC(C)CCCNC([2H])([2H])C([2H])([2H])O)=CC=N2. InChi Code: InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)/i9D2,10D2. InChi Key: XFICNUNWUREFDP-YQUBHJMPSA-N.