Demeclocycline hydrochloride

Description: Demeclocycline hydrochloride (Declomycin) is a TETRACYCLI NE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time. Target: Antibacterial, Antibiotic, ribosome. Smiles: Cl.[H][C@]12C[C@@]3([H])[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C(=O)c1c(O)ccc(Cl)c1[C@H]2O. References: Imming P, et al. Nat Rev Drug Discov. 2006 Oct,5(10):821-34.