Davercin

Davercin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It has broad-spectrum activity against various Gram-positive and Gram-negative bacteria (MICs = 0.02-50 µg/ml). Davercin is non-toxic to mice and rats (LD50s = 4.05 and 5.9 g/kg, respectively). Formulations containing davercin have been used to treat a variety of urogenital bacterial infections.Formal Name: cyclic 11,12-carbonate erythromycin. CAS Number: 55224-05-0. Synonyms: Erythromycin cyclocarbonate. Molecular Formula: C38H65NO14. Formula Weight: 759.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 15 mg/ml, DMSO: 15 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 205 nm. SMILES: C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@@H](C)C(O[C@H](CC)[C@]2(C)[C@@](OC(O2)=O)([H])[C@H]3C)=O)[C@H](C)[C@@H](O[C@@]4([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O4)[C@](C)(O)C[C@@H](C)C3=O)([H])O1. InChi Code: InChI=1S/C38H65NO14/c1-14-25-38(10)32(52-35(44)53-38)20(4)27(40)18(2)16-36(8,45)31(51-34-28(41)24(39(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-37(9,46-13)30(42)23(7)48-26/h18-26,28-32,34,41-42,45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,2. InChi Key: NKLGIWNNVDPGCA-ZDYKNUMJSA-N.