Danofloxacin (mesylate)

Danofloxacin is a fluoroquinolone antibiotic. In vitro, danofloxacin has activity against 68 field isolates of Mycoplasma species isolated from cattle, swine, and poultry with MICs ranging from 8 to 500 nM. It is protective in vivo against P. multocida, E. coli, and S. choleraesuis in mice with protective doses of 0.31, 0.40, and 2.42 mg/kg, respectively. Formulations containing danofloxacin are widely used to prevent infectious disease in livestock.Formal Name: 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-3-quinolinecarboxylic acid, methanesulfonate. CAS Number: 119478-55-6. Synonyms: CP 76,136-27. Molecular Formula: C19H20FN3O3 . CH3SO3H. Formula Weight: 453.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 25 mg/ml, Water: 20 mg/ml. lambdamax: 236, 282, 351 nm. SMILES: FC1=CC2=C(C=C1N3C[C@H]4N(C)C[C@@H]3C4)N(C5CC5)C=C(C(O)=O)C2=O.O=S(O)(C)=O. InChi Code: InChI=1S/C19H20FN3O3.CH4O3S/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10,1-5(2,3)4/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26),1H3,(H,2,3,4)/t11-,12-,/m0./s1. InChi Key: APFDJSVKQNSTKF-FXMYHANSSA-N.