D-threo-PPMP (hydrochloride)

D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor., It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP (Cay-17236). In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growth in vitro at 20 µM and significantly inhibits DNA synthesis at 3 µM. [Matreya, LLC. Catalog No. 1865]Formal Name: [R-(R*,R*)]-N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-hexadecanamide, monohydrochloride. CAS Number: 139889-65-9. Synonyms: D-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol. Molecular Formula: C29H50N2O3 . HCl. Formula Weight: 511.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: Soluble, Methanol: Soluble. SMILES: O=C(CCCCCCCCCCCCCCC)N[C@H](CN1CCOCC1)[C@H](O)C2=CC=CC=C2.Cl. InChi Code: InChI=1S/C29H50N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-28(32)30-27(25-31-21-23-34-24-22-31)29(33)26-18-15-14-16-19-26,/h14-16,18-19,27,29,33H,2-13,17,20-25H2,1H3,(H,30,32),1H/t27-,29-,/m1./s1. InChi Key: ORVAUBQYJOFWFY-ZHESDOBJSA-N.