D-Aspartic Acid

D-Aspartic acid is an amino acid and a precursor in the biosynthesis of NMDA. It is formed from L-aspartic acid by aspartate racemase and degraded by D-aspartate oxidase (DDO). It is also produced by degradation of dietary proteins or by intestinal microbiota. D-Aspartic acid binds to the L-glutamate site of ionotropic NMDA receptors (Ki = 1.6 µM). It increases the production of cAMP in rat synaptosomes when used at a concentration of 1 mM. D-Aspartic acid enhances electrically stimulated field excitatory postsynaptic potentials (fEPSPs) in rat hippocampal slices following administration in the drinking water at a concentration of 20 mM. It increases serum levels of growth hormone, luteinizing hormone, testosterone, and progesterone (Cay-15876) in rats.CAS Number: 1783-96-6. Synonyms: NSC 97922. Molecular Formula: C4H7NO4. Formula Weight: 133.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: OC(C[C@@H](N)C(O)=O)=O. InChi Code: InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1. InChi Key: CKLJMWTZIZZHCS-UWTATZPHSA-N.