Cyclopentolate (hydrochloride)

Cyclopentolate is an antagonist of muscarinic acetylcholine receptors (Kis = 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively). It inhibits carbachol-induced contraction of isolated human iris sphincter, circular ciliary muscle, and longitudinal ciliary muscle (Kbs = 7.9, 15.8, and 12.5 nM, respectively). Formulations containing cyclopentolate have been used to induce pupil dilation and to prevent the eye from accommodating for near vision.Formal Name: alpha-(1-hydroxycyclopentyl)--benzeneacetic acid, 2-(dimethylamino)ethyl ester, monohydrochloride. CAS Number: 5870-29-1. Synonyms: (±)-Cyclopentolate. Molecular Formula: C17H25NO3 . HCl. Formula Weight: 327.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly Soluble, Methanol: Slightly Soluble. SMILES: O=C(OCCN(C)C)C(C1(O)CCCC1)C2=CC=CC=C2.Cl. InChi Code: InChI=1S/C17H25NO3.ClH/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17,/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3,1H. InChi Key: RHKZVMUBMXGOLL-UHFFFAOYSA-N.