CTPB

CTPB is an amide derivative that selectively activates the histone acetyltransferase (HAT) p300, with maximal activation at 275 µM. It directly binds p300. CTPB does not alter PCAF HAT or histone deacetylase activity. It dose-dependently increases the acetylation of histones H3 and H4, with maximal effect at 200 µM.Formal Name: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide. CAS Number: 586976-24-1. Molecular Formula: C31H43ClF3NO2. Formula Weight: 554.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH7.2) (1:2): 0.33 mg/ml, DMSO: 20 mg/ml, Ethanol: 15 mg/ml. lambdamax: 258 nm. SMILES: ClC1=CC=C(NC(C2=C(CCCCCCCCCCCCCCC)C=CC=C2OCC)=O)C=C1C(F)(F)F. InChi Code: InChI=1S/C31H43ClF3NO2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-24-19-17-20-28(38-4-2)29(24)30(37)36-25-21-22-27(32)26(23-25)31(33,34)35/h17,19-23H,3-16,18H2,1-2H3,(H,36,37). InChi Key: OYBMVMAXKOGYDC-UHFFFAOYSA-N.